![]() Once you finish that cycle, you will either hop on a cruise (essentially TRT) or make use of a PCT. Who should use Enclomiphene?Īs you start using steroids, your pituitary glands will stop producing LH, resulting in a decrease in serum testosterone. If you compete in a sport governed by the WADA, then Enclomiphene is illegal without a doctors prescription. If you suffer from hypogonadism, and dislike the idea of TRT then legally, your health practitioner could potentially prescribe you with Enclomiphene. In fact, it is prescribed by doctors as an alternative to hormone replacement therapy, it’s that effective. Since Enclomiphene has been shown to increase the secretion of LH, there isn’t a need for HCG. Enclomiphene on the other hand has been shown to not have a lot of adverse effects, especially on mental health.Įnclomiphene also completely replaces the need for HCG post cycle. A study in 2011 found that 41% of subjects experienced depression, and 45% experienced mood swings whilst on Clomid. Clomid is notorious for having adverse effects on mental health (5), even coined by some as “Clomid Crazies”. When compared to Clomid, the main benefit is going to be the lack of side effects. Enclomiphene is antiestrogenic, and increases the pituitary secretion of LH, and enhances the production of testosterone. ![]() Then something to control estrogen, SERMs (like Clomid and Nolvadex) or Aromatize inhibitors ( Arimadex, Aromasin, or Letrozole).Įnclomiphene, as well as Zuclomiphene are stereoisomers of Clomiphene (Clomid), the former being isolated to function by itself. Usual suspects are HCG (Human chorionic gonadotropin) to restart testosterone production as HCG acts like LH. This is due to the back loop that leads to the suppression of LH and FSH and with prolonged use, suppression of testosterone as well (hypogonadotropic hypogonadism).Īfter you have completed your cycle you will (hopefully) make use of a PCT protocol, to restart your natural hormones as well as controlling the rise of estrogen in your body. go on a cycle) your natural testosterone does shut down. As you inject yourself with exogenous testosterone (i.e. The application for bodybuilding is obviously a bit different. ![]() By antagonizing the negative feedback on gonadotropin-releasing hormone (GnRH), it can stimulate the release of FSH. While SERMs (Selective estrogen receptor modulators) can block some of the estrogen in the body, Enclomiphene (which as in an antagonist) will have an affinity to block estrogen receptors in all parts of the body (5). Under the brand name Androxal it has recently been subscribed to men who suffer from low testosterone, want an alternative to TRT, and are not interested in Clomid (clomiphene citrate) which has enormous emotional side effects (4). Think of it as “Hey that guy stole my parking” and now you can’t get your taco at this gas station.Įnclomiphene has been shown to increase FSH (Follicle-stimulating hormone) and LH (Luteinizing hormone) as well as raise serum total testosterone in men (3). What is Enclomiphene?Įnclomiphene is what’s known as a estrogen receptor antagonist, meaning that Enclomiphene will bind to estrogen receptors in your body and prevent estrogen from actually binding to them, and therefore you have “less estrogenic” effects in your body (2). ![]() LIFING PCT FULLYour access is subject to our full Terms of Use. Prior to buying anything, check that it is compliant where you live with your current government laws. ![]() LIFING PCT PROFESSIONALIt is not intended nor implied to be a substitute for professional medical advice. Enclomiphene seems to be a good option, an estrogen receptor antagonist that can promote gonadotropin-dependent testosterone secretion – bonus it’s not a steroid and you keep your natty status.ĭisclaimer: The content on and the information included in this article is intended for entertainment and informational purposes only. Is TRT the only way? Doctors have concerns because TRT does come with side effects such as cardiovascular issues, prostate concerns, as well as worsening cholesterol levels (2). The easiest solution to this would be to go on TRT – Testosterone Replacement Therapy – where a doctor prescribes you a small amount of exogenous testosterone to mimic that of what you should be producing naturally. Low testosterone has been linked to decreased mental health, decreased sex drive, increase fat mass, loss of muscle mass, and loss of libido (2). We also see this after the completion of a steroid cycle, where the production of testosterone will be very suppressed. In males, we often see this as low testosterone which can have adverse effects on your health. Hypogonadism is the term doctors use to describe when the gonads of any human being fails to produce enough, if any, sex hormones (1). ![]()
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